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[9] Extracellular Region of homology to semaphorins (Sema domain), which includes the full α-chain and the N-terminal part of the β-chain Cysteine-rich MET-related sequence (MRS domain) Glycine-proline-rich repeats (G-P repeats) Four immunoglobulin-like structures (Ig domains), a typical protein-protein interaction region

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[98,102] In another clinical trial, a dosage of 100 mg/week of LJP-394 significantly reduced anti-dsDNA antibody levels but did not significantly prolong the time to renal flare compared to placebo

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